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At 6 hrs, Dvl2 activated sTF 3-fold and synergy between Dvl2 and Grb2 was 2 fold compared to Dvl2 alone.
Results showed that expression of miR-223 is significantly reduced over 2 fold compared to control in 85% (17/20) of ALL patients (part of data is shown in Fig. 4A).
In JEV+M animals, PSD-95 expression was significantly elevated by 2 fold compared to JEV-infected SVZ, implying the functional role of minocycline in CNS regeneration in the infected brain.
However, at the last measured time point (72 hours), CD4+CD25low T cells increased IL-2 expression almost 2 fold compared to CD4+CD25- T cells reaching significance again (t-test, p = 0.038).
The trends we observed, of increased amyloid burden (Figure 4A) and Aß42 (Figure 4C) as a result of sod2 heterozygosity, is consistent with a previous report where amyloid load was increased by approximately 2 fold compared to controls through genetic combination of sod2 heterozygotes with the Tg19959 model of AD [27].
With both epithelium estimations, EpCAM expression was significantly increased in prostate tumors by about 2 fold, compared to the 4.75 fold increase without normalization.
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Of these miRNAs, only miR-19b was increased by >±2 fold compared to global miRNA levels (Figure 3A).
Interestingly, the killing activity of differentiated HL-60 against Ca increased by only ∼2 fold compared to the one observed with undifferentiated cells [24].
While insulin supplementation was not completely necessary, it significantly enhanced force production (>2 fold) compared to differentiation without insulin.
Marked sensitization was again observed, with only a slight decrease in extent of sensitization (~2 fold) compared to a 24 h concurrent treatment.
50 100 μg/ml of oxLDL treatment or 50 μg/ml of VLDL treatment increased the expression of miR-206 in THP-1 cells by 1.5 2 fold compared to THP-1 cells incubated with native LDL (Fig. 7b).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com