Exact(1)
Successful drug delivery carriers in cancer should meet four basic requirements: (1) retain the drug during circulation, (2) evade the body's defenses, (3) access the tumor site, and (4) release the drug, specifically at the tumor site.
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Three common contexts for this departure are: Respondents (1) cannot conform to the question's terms due to the question's inadequate presuppositions; (2) defer a straightforward or type-conforming answer; and (3) evade the question.
3) Evade Hard Choices: You'll hear all the excuses: "This isn't the right time". "There's nothing I can do". Sure, there may be more immediate priorities.
These mechanisms were shown to help bacteria survive antibiotic stress [ 2], evade the immune system [ 3], and better utilize their surroundings [ 4].
K5 is a modulator of immune recognition (ubiquitin ligase) that helps HHV8 evade the host's immune system during lytic replication [ 21].
However, many viruses, including poxviruses [ 3, 11], evade the T cell-mediated immune response, primarily by decreasing the levels of surface MHC I, thus reducing the presentation of pathogen-derived antigens [ 12] to escape cellular immunosurveillance mechanisms [ 13].
These are potentially examples of clients that have, at least partially, lost their dependency on Hsp90 and evade Hsp90 inhibition effects, which could impair effectiveness of cancer treatment.
HIV-1 evades antibody-mediated neutralization in many cunning ways.
Backstory Ronnie Biggs, 76, evaded Slipper and Scotland Yard for more than 30 years.
Rasaiyaah, J. et al. HIV-1 evades innate immune recognition through specific cofactor recruitment.
Earlier in the day Neilson, 36, evaded waiting media at the club's Riccarton training ground with the help of a masked decoy.
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