The interns would likely prescribe antibiotics (71, 87.6%), nonsteroidal analgesics (66, 81.4%), diuretics (55, 67.9%), sedatives (52, 62.9%), and insulin and oral hypoglycaemics (43, 53%) with confidence and unsupervised.
The 10 most frequently prescribed antihypertensive regimens, ranked in order of prescribing frequency, were as follows: CCBs (17.7%), beta-blockers (14.5%), ACEIs (8.2%), CCBs + beta-blockers (7.7%), others (5.3%), diuretics (4.4%), CCBs + ACEIs (4.0%), ARBs (3.0%), CCBs + ARBs (2.6%), beta-blockers + diuretics (2.4%).
Formulae (1) Urinary Excretion = Total urinary output Total liquid administered × 100%% (2) Diuretic Action = Urinary excretion of treatment groups Urinary excretion of control group (3) Diuretic Activity = Diuretic action of test drug Diuretic action of standard drug Sodium, potassium and chloride levels of urine and the plant extract were analyzed.
The patients were orally administered ACE inhibitors (n=15), angiotensin II receptor blockers (n=55), calcium channel blockers (n=37), β-blockers (n=48) and diuretics (n=46).
Thus, although widely used [27, 45], diuretics have failed to demonstrate any benefit in preventing AKI, limiting the risk of RRT or fastening renal recovery [46].
Because AKI with fluid overload is associated with higher mortality rates [104, 107], diuretics can be proposed for treating fluid overload.
Among them: immobilization (due to neurologic condition, sedation, or paralysis), catabolic state and endocrine imbalance, nutritional depletion, sun deprivation, and at times, use of medications that promote bone loss such as steroids, antiepileptic drugs [17], diuretics [18], or heparin [19].
If AKI progresses to stages 2 and 3, diuretics are discontinued if this has not already occurred, and albumin should be administered at 1 g/kg for 2 days.
Antihypertensive agents evaluated include beta-blockers [21] [27], [33], diuretics [23], ACE inhibitors [23], Ca channel blockers [23] and unspecific antihypertensive agents [34].
