Sentence examples for 2 attenuates from inspiring English sources

Additionally, we propose that therapeutic targeting of HSulf-2 could lead to improved clinical outcome in patients with breast cancer Silencing of heparan sulfatase 2 attenuates breast cancer growth and inhibits basement membrane disruption in a matrix metalloprotease dependent process.

In the present study, we hypothesized that the antioxidant transcription factor, Nrf2 (nuclear factor erythroid-derived 2 like 2), attenuates glioma cytotoxicity to Carmustine (BCNU), a widely used chemotherapeutic agent known to modulate cellular oxidative balance.

We used this transgenic model in combination with the Mlc2v- Cre k /+ transgenic mouse to force myocardial specific p57 Kip 2 expression in the embryonic and adult heart [ 21] and we show that myocardial specific expression of p57 Kip 2 attenuates hypoxic-ischemic injury in the adult mouse heart.

However, less nucleophilic alkynes, including diaryl and aryl/alkyl-substituted alkynes, did not react with 2. The significant B=Npyridyl character observed in 4 and calculated in the ring-opened borenium-cation forms of 1 and 2 attenuates the electrophilicity at boron and thus limits the scope of the reaction with respect to the alkyne substrate.

Adjustment for demographic and metabolic factors (multivariate model 2) attenuated the ORs (1.18 [0.80–1.74] and 1.29 [0.91–1.82], respectively).

Open image in new window Figure 5 SIRT6 attenuates AKT signaling after H2O2 treatment.

Previously, we reported that H2S attenuates liver dysfunction arising from LPS-induced systemic inflammation [1].

Decreased activity of PDPK1 attenuates neutrophil chemotaxis in response to fMLP [40, 41].

C. CR50 attenuates HNP-stimulated platelet aggregation in ADP-primed human platelet rich plasma.

It is worth noting that neither knockout/knockdown nor overexpression of APIP12 attenuates Piz-t resistance.

Our results suggest that administration of β-casomorphin-7 attenuates renal interstitial fibrosis caused by diabetes.