Sentence examples for 1 tk from inspiring English sources

The inhibitory activity of araT and BVaraU to dThd phosphorylation by other related nucleoside kinases, including herpes simplex virus type 1 TK, varicella zoster virus TK, and cytosolic TK-1, was completely annihilated upon 2′-O-acyl substitution (ic50 ≥ 1000 μM).

The downlink signal is x, and the precoding vector of the k th BS is t k = [tk 1, tk 2,..., t kM ] T with a power constraint ║t k ║ = 1.

Additionally, plasmid DNA containing the HSV-2 tk gene, but not type 1 tk or LacZ DNA, was shown to form an anisomorphic DNA stucture.

3′-deoxy-3′-[F]fluorothymidine uptake is dependent on thymidine kinase 1 (TK) activity, but the effects of chemotherapeutic agents are unknown.

All active compounds (61 total) were listed as the following: 1) TK: 10, 2) ER α antagonists: 11, 3) ER α agonists: 10, 4) hDHFR: 10, and 5) NA: 20.

However, alignment of the tk sequences showed that the type 2 gene had at least eight distinct stretches containing between 7 and 13 G-C bases, whereas the overlapping region in the type 1 tk had four or less G-C bases.

FLT crosses the cell membrane and becomes phosphorylated by thymidine kinase 1 (TK-1), which is the first enzyme in the salvage pathway of thymidine synthesis as part of the DNA synthesis.

3′-deoxy-3′-[F]fluorothymidine is phosphorylated by the cytosolic enzyme thymidine kinase 1 (TK-1) into FLT-monophosphate, which is trapped in the cell (Direcks et al, 2006).

HSV-1 TK selectivity, based on uptake, ranged from 10too 140, with IVDU being most selective for HSV-1 TK expressing cells, followed by IVFRU, FIRU, FIAU, IVFAU and finally IUDR.

Furthermore, the biologic activity of products delivered by Nef7-based VLPs was demonstrated by tagging Nef7 with the herpes simplex virus-1 thymidine kinase (HSV-1 TK).

In summary, these nucleosides are unpredictably cytotoxic to the various cell lines studied, and this unpredictability extends across the HSV-1 TK expression characteristic; their uptake by cells engineered to express HSV-1 TK is also dependent on the molecular construction of the gene cassette carrying the viral TK gene.