Sentence examples for 1 mediates from inspiring English sources

Current data support the idea that hypothalamic neuropeptide orexin A (OxA; hypocretin 1) mediates resistance to high fat diet-induced obesity.

However, ET-1 mediates many complex events in other tissues.

These results establish that PU.1 mediates chromosome looping and functions as a master regulator of HSC proliferation.

The N-terminus intracellular region (cytoplasmic domain) of LOX-1 mediates receptor internalization and trafficking, potentially through intracellular protein interactions.

Platelet-endothelial cell adhesion molecule-1 (PECAM-1) mediates the transendothelial migration of circulating leukocytes, a characteristic change in vascular inflammation leading to atherosclerotic plaque development.

Stabilin-1 mediates internalisation of acLDL and its delivery to early endosomes, and it is translocated together with its ligand to the late endosomal compartment.

In particular, VCAM-1 mediates firm adhesion, tethering, rolling of monocytes and facilitates their transendothelial migration at the developing atheroma [26].

For example, VAP-1 mediates lymphocyte binding to the vascular endothelium in rejected kidney allografts as well as in the liver allograft in rats [32, 33].

ICAM-1 mediates inflammatory responses via adhesion of leukocytes to activated endothelium and subsequent leukocyte transmigration through the pulmonary endothelial layer [55].

Vascular cell adhesion molecule-1 (VCAM-1) mediates cell adhesion and transendothelial migration of leukocytes.

Others have shown that HO-1 mediates VEGF stimulated angiogenesis [19].