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The QTL confidence interval (95%) was estimated by the LOD drop-off method (1 LOD was used).
Confidence intervals were determined using the "2 lod drop off" criterion and assuming 1 LOD = 4.61 LRT [ 53].
Then, QTL density at each location on the map was determined by integrating the overlapping 1 LOD ranges.
A heat map of the overlapping 1 LOD confidence intervals provides an overview of the distribution of QTLs.
Another gene, located in the minus 1 LOD support, contains CNV polymorphisms between the two mouse strains.
1) LOD determinations, with a dilution series of all strains, were tested by using real-time RT-PCR (15 ).
Similar(51)
The limits of detection (LODs) and quantification (LO Qs for 1-hydroxypyrene were 0.20 µg mL−1 (LOD) and 1.35 µg mL−1 (LO Q, and 0.03 µg mL−1 (LOD) and 0.10 µg mL−1 (LOQ) for 1-hydroxyphenanthrene, respectively.
These validation parameters reached 1.6 μg L−1 (LOD) and 5.4 μg L−1 (LOQ) by using 3σ and 10σ approaches.
The Ppy/Au/MA exhibits sensitivity of only 0.27 mA cm−2 mM−1, LOD of 5 μM and linear range of 10 μM to 2.2 mM.
Based on a signal-to-noise ratio of 3 1, LOD was found to be 0.1 μg/mL for brimonidine tartrate.
Based on a signal-to-noise ratio of 3 1, LOD was found to be 0.1 and 0.02 μg mL-1 for pheniramine maleate and naphazoline hydrochloride, respectively.
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