The prototypical CD1d agonist, α-galactosyl ceramide (α-GalCer) 1, instigates a powerful immune response and the generation of a wide range of cytokines when it is presented to iNKT cell TCRs by CD1d molecules.
Each mimetic leads to the stabilisation of HIF-1α, through inhibition of the prolyl hydroxylases which in the presence of O2 instigate the degradation of the transcription factor subunit [29,30].
[Pausing for thought] Where is the toilet?" Boy 2 (instigating an exchange of dead arms) "You should have gone".
By this time, however, his standing outside Egypt had been lost; and in June 1879, Sultan Abdülhamid II (reigned 1876 1909), instigated by France and Britain, deposed him in favour of his son, Muḥammad Tawfīq.
Guest's professed ignorance of even the most basic details of a "huge asset-stripping controversy in the 70s", instigated by someone he has met several times, exasperates his friend Toby, who gives up and says "you were probably doing Chaucer that week".
This consequence supports the FESEM outcomes shown in Figure 4, instigated from one-step template-assisted electrodeposition process for ultrathin ZnO NW arrays.
Police believe the stabbing victim, identified as Burbank resident Ricardo Ramirez, and his associate Maximo de los Santos Jr., 21, instigated the fight with a rival gang.
There's a dinner at 165 instigated by Edward, Duke of Kent Blake Ritsonn), who wants to influence a Daily Mail editor against Edward VIII's history-making infatuation with American-born divorcee Wallis Simpson.
In the early 50s, Mohammed Mossadegh, the country's democratically elected prime minister, began making efforts to nationalize the country's oil industry, which had been largely controlled by the British and French until the CIA and MI6 instigated a coup against him in 1953.
In close connection to membrane binding and inclusion formation, we found that wild-type synphilin-1 instigates a higher toxicity than the mutant protein.
