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For the 20 mg/kg q2w group (cohort 2), PK samples were collected up to 336 h post end of infusion following the first (cycle 1, day 1) and fifth (cycle 2, day 1) infusions.
Over the follow-up period, a mean (± SD) of 7 ± 3 infusions was observed per patient among those in either the first- or subsequent-line infliximab cohorts, 3 ± 1 infusions were captured for the rituximab cohort and 10 ± 4 infusions were noted for the abatacept cohort.
Similar(58)
Fig. 1 Infusion line setup.
The between-group differences in total hip bone mineral density at 3 years were 3.8% in those receiving 1 infusion and 6.2% in those receiving 3 infusions.
INTERVENTION: The intervention of the study consisted of 1 infusion of zoledronic acid or placebo.
OBJECTIVE: The objective of the study was to assess fracture incidence after only 1 infusion of zoledronic acid.
In a mouse model of thrombosis, DNase 1 infusion disassembles NETs and prevents thrombus formation [164].
Three of the 28 patients (10.7%) missed 1 infusion.
We further characterized the effects of GLP-1 on feeding in rats by testing (1) the effects of brief, prandial GLP-1 infusions, designed to mimic meal-related GLP-1 secretion, on spontaneous feeding parameters, and (2) hepatic portal vein (HPV) vs. inferior vena cava (VC) infusions.
During the last 2 hours (120 to 240 minutes) of glucagon infusion, EGP in the diabetics tended to be higher than controls during the 3 lower glucagon infusion rates and this difference reached statistical significance (P [lt ].05 to.01) during the 6 and 8 ng [middot] kg[minus ]1 [middot] min[minus ]1 infusions.
I will probably have 10 infusions this year.
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