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In this paper, three novel interval type-2 fuzzy membership function (IT2 FMF) generation methods are proposed.
Blood samples were collected from all FMF patients and healthy subjects, and fecal samples from 6 FMF patients and 3 healthy controls (Table 1).
Homozygosity of R202Q has been detected in four of 26 FMF patients and none of 60 healthy individuals (p = 0.007, [49]).
For this, freshly voided feces were collected into sterile containers from 12 FMF patients in remission, three patients in the acute stage of FMF, six healthy Armenians, and one healthy subject of non-Armenian origin (Table 1).
A total of 19 FMF patients and eight healthy individuals were genotyped for mutations in the MEFV gene and gut bacterial diversity was assessed by sequencing 16S rRNA gene libraries and FISH analysis.
The study was approved by the local ethical committee at IMB. Venous blood samples were obtained from the clinically confirmed 19 FMF patients and eight healthy controls to reveal the MEFV mutation carrier status.
In order to minimize inter-individual variations, 16S rRNA gene libraries were constructed from fecal samples of 12 FMF patients in remission, three patients in the acute stage of FMF, six healthy Armenians, and one healthy subject of non-Armenian origin.
A total of 157 FMF patients (78.1%) and 233 (73%) unaffected FDRs reported back pain.
Of the 70 FMF patients with musculoskeletal findings 55 agreed to participate in the study.
Minor criteria were: 1) recurrent febrile episodes; 2) erysipelas-like erythema; and 3) FMF in a first-degree relative.
MRI analysis of the SIJs was obtained in 23 out of the 29 FMF patients in our cohort who had IBP, but not radiographic sacroiliitis.
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