Sentence examples for 1 disrupts from inspiring English sources

We previously showed that knockdown of netrin 1a, a zebrafish ortholog of mammalian netrin 1, disrupts PAC development (Wilson et al., 2006).

Recently, Bond et al. reported that a T>G polymorphism at position 309 downstream from MDM2 intron 1 disrupts an Sp1 regulatory element and the T allele thus has a strikingly lower promoter activity compared with the G allele [ 6].

Competitive ELISA using antibodies from a chicken injected with α-peptide 1 conjugated to the carrier show that free peptide 1 disrupts binding of these polyclonal antibodies (anti- 1) to immobilized 1 more effectively than α/β-peptide 2 disrupts this binding.

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This result suggests that compound 1 disrupted STAT3-STAT3 dinerization in a dose-dependent manner in cellulo.

Much like H4 K16 acetylation, H3 K79 methylation disrupts Sir3 binding.

Acetylation of residue K305 disrupts the tetramer formation.

Depletion or inhibition of TIP60 disrupts the regulatory relationship between UHRF2, H3K9ac and H3K14ac.

It is known that Par-1 promotes Delta ligand localization on the lateral membrane in Drosophila and the depletion of Par-1 disrupts Notch signalling [21].

It is more likely that bafilomycin A1 disrupts Happ1 function by disrupting lysosomal pH.