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Fig. 1 Deletion of rha1 and lra3 genes: (a) Deletion cassette for disruption of the catabolic l-rhamnose pathway in A. niger (b).
Each of these genes showed 1 deletion each.
These equated to 2 SNVs and 1 deletion.
All patients with the intron 1 deletion were sequenced.
As seen in Figure 1, deletion of the GH3 domain prevented Reaper from inducing mitochondrial fragmentation.
All control individuals with the intron 1 deletion were also sequenced.
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By contrast, endothelial Trem-1 deletion favored the accumulation of reparative cells (Ly6Clow monocytes).
S54 Targeted endothelial TREM-1 deletion protects mice during septic shock.
Trem-1 deletion altered inflammatory cells mobilization and recruitment in lungs and spleen and favours the accumulation of reparative cells (Ly6Clow monocytes and M2 macrophages) in the lungs.
As aforementioned, the hcf-1 deletion mutants are homozygous viable.
Two large hcf-1 deletion mutants (pk924 and ok559) are viable but display reduced fertility.
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