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After all rats showed stable extinction values (<10 active responses, 5 consecutive sessions), rats were tested for cue-induced relapse (1 hr duration, no reward, 1 cue series at start of session and the ability to respond for the compound cue on an FR1 schedule).
Animals were considered visually impaired if they failed to find the platform within the allotted 60 s on 2 out of 3 trials on day 1 (cue learning), and on 3 out of 3 trials for learning days 3 and 4. Using this criterion, 6 aged animals, 3 AC and 3 AP, were excluded from the behavioral analysis.
Reward circuits compared the monkeys' eye position signals with the position signals of the stationary spot during the initial fixation, cue 1, cue 2, and the 2 delay periods and with the correct target spot during the action period (Fig. 1).
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It is measured on a scale from –1 (cue-wise search) to +1 (option-wise search).
Our newly introduced organization index, OI, allows quantifying information organization on the same scale as the SI, ranging from –1 (cue-wise grouping) to +1 (option-wise grouping).
Session 1 cues were presented in sequence i.e., 40 presentations of cue 1, then 40 of cue 2 then 40 of cue 3. We used all three sessions for the behavioral analysis.
In session 1, cues were presented in sequence i.e., forty presentations of cue1-reward, then forty of cue 2-reward then forty of cue 3-reward.
The cells were treated with 0, 2.5, 5, and 7.5 μM CuE for 24 h.
By Betsy Morais October 17, 2012 Cue triumphant music.
But Ronaldinho has fallen to No. 3! Cue the parity trumpets!
Figure 7 CUE throughput.
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