Compared with NPH, detemir was less costly and more effective in 3/14 cost effectiveness analyses and glargine was less costly and more effective in 2/8 cost effectiveness analyses.
Glargine was not cost effective compared with detemir in 2/2 cost effectiveness analyses.
‡Estimated at £20 000 cost effectiveness threshold.
Other knowledge gaps identified included risks and harms [ 18, 21, 22, 25], user satisfaction and acceptability [ 18, 21, 22], cost effectiveness [ 18, 21, 25], and dose response [ 23].
Kidney transplantation is the preferred treatment option for end stage renal failure in terms of mortality [ 1, 2], cost effectiveness [ 3], and improvement in quality of life [ 4].
The issues were heavily analysed over several years, including demand estimates [ 21], cost effectiveness analysis [ 22], policy analysis [ 23] and a public opinion survey [ 24].
Recent reviews of published PCV7 cost effectiveness evaluations highlight the contributions of herd protection, prevention of pneumonia and AOM and vaccine coverage of non-PCV7 serotypes [79,86-89].
Assuming that each child who recovers has a life expectancy of 33.3 disability adjusted life years [ 5], cost effectiveness was also expressed in dollars per DALY gained.
If the dispensable shelf life of an ophthalmic preparation requires its disposal before the entire bottle of drug solution has been used [ 6], cost effectiveness can be affected.
30 Cost effectiveness may be reported in terms of many different outcome measures, ranging from biomedical markers to more final health outcomes.
According to calculations not presented in Table 1, cost-effectiveness ratios at health centres were also lower than hospital outpatient departments.
