Sentence examples for 1 chaperone from inspiring English sources

Three major types of autophagy exist in eukaryotes: (1) chaperone mediated autophagy (CMA), (2) microautophagy, and (3) macroautophagy, hereafter referred to as autophagy [ 10].

Reviewer #1: Chaperone proteins have been found to play important roles in facilitating the formation of signaling complexes that could include receptors, G protein subunits and effectors.

There are some expectations of this simple model:(1) chaperone variants with a larger or stronger hydrophobic patch will have enhanced affinity for client proteins, and (2) client proteins are likely to interact with regions on the 3D structure of the chaperone that are adjacent to the sites mutated in our selected Spy variants.

We have re-written this part of the Introduction to highlight the facts that 1) chaperone overexpression has not been demonstrated to resolve amyloid in vivo and 2) amyloid clearance mechanisms must exist in vivo, although they are ineffective against continuously expressed, wildtype amyloid proteins.

Several mechanisms account for the cytoprotective effect of Hsp27, including: (1) chaperone inhibitor of protein misfolding; (2) inhibition of key effectors of the apoptotic machinery at the pre- and post-mitochondrial level and (3) proteasome-mediated degradation of proteins under stress conditions.

Make sure there is at least 1 chaperone at your party.

Fig. 5 The Hop/Sti1-HSP90 complexne complex facilitates the maturation and transport of PRRs.

The Hop/Sti1-HSP90 complexne complaysplans an important and conserved role in the maturation and transport of PRRs.

Mechanistically, PHB forms protein complexes with HIRA, a histone H3.3 chaperone, and stabilizes the protein levels of HIRA complex components.

However, the histone H3 H4 chaperone ASF1A is an important factor regulating chromatin assembling and gene transcription, while it is currently unclear whether ASF1A is involved in cancer pathogenesis.

For instance, ERAD of Gap1 occurs when the Shr3 chaperone is deficient [2].