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The purified 11β-HSD 1 catalyses this reaction in a stereospecific manner.
The 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) catalyses the reduction of the weakly active estrone (E1) into the most potent estrogen, 17β-estradiol (E2).
Sphingosine kinase 1 catalyses the formation of the bioactive lipid, sphingosine 1-phosphate and is a target for anti-cancer agents.
Microsomal prostaglandin E2 synthase (MPGES) 1 catalyses its formation from cyclooxygenase-derived PGH2 and is an inflammation-induced enzyme overexpressed in synovial tissue of RA patients [10].
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyses the intracellular conversion of inactive cortisone to cortisol.
Polyphosphate kinase 1 (PPK1) catalyses the synthesis of polyphosphate (poly P) which is a linear polymer composed of several orthophosphate residues.
The ethylmalonic encephalopathy protein 1 (ETHE1) catalyses the oxygen-dependent oxidation of glutathione persulfide (GSSH) to give persulfite and glutathione.
Cytochromes P450 catalyse extremely diverse and often complex regiospecific and/or stereospecific reactions in the biosynthesis or catabolism of plant bioactive molecules.
Lysyl hydroxylases 1, 2, and 3 catalyse the hydroxylation of specific lysines in collagen.
Progesterone 5β-reductases (P5ßRs) catalyse one step in the stereospecific biosynthesis of cardenolides (potent repellents of herbivores and pharmaceutical stimulants of disordered heart muscle cells).
The SET domains of vertebrate Smyd1, Smyd2 and Smyd3 catalyse methylation of H3-K4 [8], [7], [8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com