Your English writing platform
Discover LudwigExact(8)
As we summarize in Table 1, BMP proteins and BMP signaling components are arising in recent studies as novel biomarkers with important therapeutic implications for astrocytic glioma.
alk8 codes for a type 1 BMP receptor, through which Bmp2b and other BMPs act; the similar behavioural phenotype in rescued swr/bmp2b and laf/alk8 fish suggests that semicircular canal duct outgrowth requires BMP signalling through Alk8.
The same was observed for all the remaining proteins as IGF 1, BMP, Coll 1A and PDGF.
(1) BMP signaling represses the transcription of its extracellular inhibitor sog, a feature so far not observed in other insects, but characteristic for spiders and vertebrates.
In the genetic disease FOP, the ectopic ossification of soft tissues in patients is the result of a dominant mutation in ACVR1/ALK2, a type 1 BMP receptor [ 44].
From their RNAi data, the authors conclude that (1) BMP signaling is active throughout the DV axis and must be repressed ventrally through expression of sog to allow ventral patterning; and (2) Toll is not required to support any cell types but is required for symmetry breaking.
Similar(52)
Furthermore, LL-37 induces migration of human peripheral blood monocytes, neutrophils, CD4+ T cells, and mast cells [12], [13], [20], [21] and influences the expression of over 40 genes in murine RAW 264.7 macrophage cells, in which some of these gene products are involved in bone formation, including the bone morphogenetic protein (BMP) 1, BMP-2, and BMP-8a [22].
Moreover, it was earlier reported that bone morphogenetic protein 1 (BMP-1) is responsible for this proteolytic cleavage of laminin γ2 [24], [24].
One candidate metalloproteinase responsible is the c-terminal procollagen endoproteinase, Bone morphogenic protein 1 (BMP-1).
The expression of S100A4, TGF- β 1, BMP-7, Smad2/3, Smad1/5/8, and p16INK4a was determined by western blot and real-time RT-PCR.
POSTN has been shown to interact with bone morphogenetic protein 1 (BMP-1) and fibronectin that consequently leads to the activation of LOX in the ECM and enhanced collagen crosslinking (Maruhashi et al, 2010).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com