Sentence examples for 1 apc from inspiring English sources

Our data suggest APC plays two roles: (1) APC promotes efficient Axin multimerization through one known and one novel APC Axin interaction site, and (2) GSK3 acts through APC motifs R2 and B to regulate APC Axin interactions, promoting high-throughput of βcatenin to destruction.

We removed the description of "conformational change" from the Abstract, revising it as follows: "Our data suggest APC plays two roles: (1) APC promotes efficient Axin multimerization through one known and one novel APC Axin interaction site, and (2) GSK3 acts through APC motifs R2 and B to regulate APC Axin interactions, promoting high-throughput of βcatenin to destruction".

The four pairs with top gene interaction effects from it: 1) APC and NFKB1; 2) and1 aNFKB1KB1; 3) DVL1 and MYD88; and 4 PPP2CAandnd WNT10B.

Adenomatous polyposis coli 1 (APC 1) was nonsignificantly downregulated (P =.114) to exposure of both doses of ITCM.

Finally, 1 APC was replaced because of breakage observed in a 34-year-old male following massive polyethylene cup wear.

3) Figure 1 figure supplement 1: APC is still active in quiescent extracts based on an assay performed with degradation of securin.

Whole blood (100 μL) and splenic lymphocytes (10) were triple-stained with (1) APC-anti-CD3, FITC-anti-CD45RA and PE-anti-CD161a, or (2) APC-anti-CD3, PE-anti-CD4 and FITC-anti-CD8a (all from BD Biosciences, San Jose, CA, USA) for 30 min at 4°C in the dark, then washed with PBS and resuspended in FACS staining buffer (BD Biosciences).

In yeast only one APC ortholog exists (Sal1p) [9], whereas in humans four genes encode full-length APC paralogs; SLC25A24, SLC25A25, SLC25A23 and SLC25A54 encoding for the protein short calcium binding mitochondrial carrier (SCaMC) isoform 1 (APC-1), SCaMC-2 (APC-3), SCaMC-3 (APC-2) and SCaMC-1L, respectively [3,10,11].

The proteins that regulate its expression in Drosophila are homologues of vertebrate proteins (Wnt-1, APC) that have been implicated in many forms of human cancer.

Sections incubated at room temperature for 1 h with the following antibodies (1 100, all from Biolegend): FITC anti-mouse CD3, PerCP/Cy5.5 anti-mouse GR-1, APC anti-mouse c-Kit and counterstained with DAPI.

In intact planarians depleted of β-catenin-1, APC, or ptc, infliction of lateral H-wounds induced tissue outgrowths, such as small heads in β-catenin-1 RNAi planarians.