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Additionally, compound 1 antagonized STAT3 dimerization and STAT3 tyrosine phosphorylation in cellulo.
It is also visible from the network that subset 1 antagonizes the other two.
Like SFRPs, WNT inhibitory factor 1 antagonizes Wnt signaling by binding to WNTs.
MDM4 is regarded a negative regulator of p53 and cooperates with MDM2 to antagonize p53 [ 8- 10].
AtWRKY40 and AtWRKY60 proteins antagonize AtWRKY18 during P. syringae infection.
Soluble frizzled-related proteins (Sfrps) and WIF-1 antagonize Wnt-Fz interactions whereas Dickkopf (Dkk) antagonizes LRP5/6 [7].
Msn2 and Msn4 antagonize PKA-dependent growth [60].
The negative Smad genes (Smad6 and Smad7), antagonize and block TGFβ superfamily signaling [13] [16].
We conclude that 21OH-6,19OP and RU486 antagonize GR by different mechanisms.
In contrast, RSPO1, WNT4, beta-catenin, and FOXL2 antagonize SOX9 and FGF9 to promote ovarian differentiation [4], [7], [8].
Does RING1B antagonize binding of KDM2A?
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