Sentence examples for 1 alter from inspiring English sources

Murphy MP, Uljon SN, Golde TE, Wang R. FAD-linked mutations in presenilin 1 alter the length of Abeta peptides derived from betaAPP transmembrane domain mutants.

Here we report that profilin 1 and related protein profilin 2 are novel stress granule-associated proteins in mouse primary cortical neurons and in human cell lines and that ALS-linked mutations in profilin 1 alter stress granule dynamics, providing further evidence for the potential role of stress granules in ALS pathogenesis.

Accordingly, a visual cycle modulator (VCM) – with no known direct effect on retinal vasculature – was administered to "50/10 model" OIR Sprague Dawley rats to test the hypotheses that it would 1) alter rod function and 2) consequently alter vascular outcome.

In the literature, it has been reported that CBZ may: (1) alter the levels of various hormones (testosterone, LH, FSH, GnRH); (2) negatively influence testicular steroidogenesis; (3) have androgenic effects acting directly in the androgenic receptors and/or increasing the expression of androgen receptors.

Specifically, phonotrauma can (1) alter the tissue's physical properties by disrupting intracellular adhesion [1], and (2) modulate the tissue's cellular/molecular responses by altering gene expression [3].

It can: (1) alter the localization of ion channels, and (2) cause abnormal expression of ion channel subtypes, as reported in pathological studies of inherited demyelinating neuropathies and in animal models.

We hypothesized that depressed individuals would show 1) altered hippocampal response to exogenous administration of cortisol, and 2) altered effects of cortisol on learning.

After all, most of the measures — Propositions 1A through 1F — alter laws or rules they previously passed by initiative.

We have shown that 17 β-estradiol (E2) alter the ductulogenic pattern of these cells.

The two alleles of the SNP rs6746030 alter the coding sequence of the sodium channel Nav1.7.

The two T1D-associated intronic SNPs within IFIH1, rs35337543 (IVS8+1) and rs35732034 (IVS14+1), alter the 5' base of intron 8 and intron 14 consensus splice sequences, respectively, and were predicted to alter splicing of the intron [4].