Exact(1)
However, the deletion of ANK repeat 1 (abrogated) abrogated its interaction with uMtCK.
Similar(59)
Deletion of RING finger domain in UHRF2 abrogated the effect.
Among them, L135G abrogated fusion and reduced replication in C6/36 cells, but only slightly reduced the mosquito infection rate.
Intriguingly, FL-VASP/239D abrogated the stimulatory effects of FL-VASP/WT and FL-VASP/239A cells on PKG activity.
Notably, overexpression of ATG12 abrogated the neuronprotective effects of miR-23b on TBI-induced neurological and cognitive impairments.
As expected from their interaction specificity (see Table 1) INr-1 abrogated the inhibitory effect of the Rev 53 67 peptide while INr-2 that exerted by the Rev 13 23 peptide (fig 3A and B) The INrs did not, by themselves, have any effect on IN enzymatic activity (Fig 3E) or on Rev protein activity which was estimated by a previously described method [25] (not shown).
Furthermore, Wortmannin and LY294002 abrogated CD28SA-mediated IL-2 synthesis.
Similarly, SB203580 abrogated PIM2 triggered IκBα phosphorylation (Figure S16B).
Expression of UNCL.F1 abrogated this effect (Figure 6A).
In addition, PI3K inhibitor, LY294002, abrogated PIM2 triggered cell-surface expression of MMP-9 (Figure S5).
As shown in Fig. 2C, BRAFV600E abrogated the RASSF1A-induced FoxO3 transactivation.
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