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This problem has been inadvertently highlighted in a recent observational sub-study of the OPTIMISE trial [54], which included 100 of the 368 patients allocated to the CO-guided hemodynamic therapy algorithm [57].
The results of the OPTIMISE study through 12 months of follow-up are presented here.
All patients with T2DM (insulin treated or not), aged ≥18 years were eligible for the OPTIMISE study.
To minimise measurement variability, a central laboratory was identified for measuring HbA1c and lipids in the OPTIMISE trial.
In the OPTIMISE study, benchmarking refers to the process of comparing critical quality indicators with the results of peers.
Baseline results from the OPTIMISE study demonstrated that target achievement for three critical quality indicators of vascular risk was suboptimal in a primary care setting (16).
Similar(40)
Powerful computers then crunch the data, optimise operations and tell the authorities about incipient problems.
Many studies in the literature optimise operation of individual components along the CCS process chain for base-load/design conditions.
Another five genes help the yak optimise the energy it gets from its food, essential in the winter when food is scarce.
In addition, the SMEs optimise the required technology so that medium- to high-throughput measurements become possible.
Nowadays, however, fewer patients receive HES with consideration of its detrimental effect on the kidney, as in the OPTIMISE study [ 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com