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Pharmacological and genetic inhibition of STAT3 stimulated the activating phosphorylation of PKR and consequent eIF2α hyperphosphorylation.
Karyogamic syncytia exhibit the activating phosphorylation of ATM on serine 1981 ATMS1981**) within their nuclei.
Depletion of PML, TOPBP1, NBN or ATM inhibits the activating phosphorylation of CHEK2.
Thus, the activating phosphorylation of LIMK1T508 is important for the interaction of LIMK1 with fascin-1.
Usually, the activating influence becomes operational at another time scale than the inhibiting influence.
We have observed a significantly higher frequency of the activating gene KIR3DS1 in HSNs.
However, the activating phosphorylation of threonine-696 of MYPT was not prevented by Bay11-7082.
All of the active kinases in this experiment harbored the activating S177E/S181E mutations.
The surface functional groups of the PVA-ACFs depend on the activating agents.
These results corroborate the observation that Chk1 inhibition causes the activating phosphorylation of p53 (Fig. 3C).
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