Exact(4)
The combination ST 124/serotype 14 found in the gorilla, a dog and, as an SLV, in the laboratory rats has been reported from Germany, Sweden, UK, Denmark, Finland, Norway, The Netherlands, Australia, Canada, and Poland and is associated with meningitis, bacteremia, pneumonia and otitis media in human isolates, as well as with carriage (www.mlst.net).net
In particular, isolate Cam033 (SIT405) differed by a single locus variation (SLV in MIRU02) from isolate Cam038 which belongs to the EAI2_Manilla subfamily.
In-depth analysis of these NMR data reveals interesting conformational changes that are consistent with a kinetic model in which formation of an initial contact between the loops of SLI and SLV in the natural VS ribozyme destabilizes the SLI loop closing base pairs and triggers the helix shift in SLI.
Chemical modifications experiments are also in agreement with the observed U-turn structures in both SLI and SLV, in particular the two hydrogen bonds commonly found in U-turn structures: U 2′ OH to R N7 and U H3 to R 3′-phosphate.
Similar(56)
SS18.6 had the highest number of SLVs in cluster B and was detected in 5 countries in Asia and Africa.
The finding of high average numbers (≥4) of nucleotide differences in the nonidentical alleles of SLVs in the total E. faecium population as well as in complex-17 also points towards frequent recombination.
Therefore, most alleles of SLVs in complex-17 and in the other complexes have arisen by recombination in the initial stages of diversification rather than by de novo point mutation.
Lexus refers to its SUV as an SLV, as in Sport Luxury Vehicle.
In this study, whole genome resequencing analysis using an Illumina platform was performed to more deeply investigate the genetic aspects of SLV expression in comparison with the parental Brown line (BL) of chickens from which the SL was originally derived.
Previous NMR studies of the free SLI and SLV hairpins derived from the VS ribozymes have provided a wealth of structural information for the SLI and SLV loops in their free forms.
These spectra confirm W C base pairing in the SLIsbΔIa stem (N-SLIsbΔIa/SLV complex), the SLV stem (SLIsbΔIa/N-SLV complex), and at the kissing-loop junction (N-SLIsbΔIa/N-SLV complex).
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