In line with this finding, school SES in our study was also a stronger variable than the student-level variable of family SES in regard to predicting the probability of a student being a reader with high proficiency.
We examined the association between individual, parental and life-course SES in relation to breast and cervical cancer screening using education-based and employment-based measures of SES.
As described above, Smad3 could be used to define SEs in mESC.
Another recent study has demonstrated that Cdk8 regulates the key genes associated with SEs in acute myeloid leukaemia (AML) cells55.
To test this in more differentiated cells, we identified and characterized SEs in pro-B cells by only using Smad3.
Our feature ranking and analysis can serve as a resource to further characterize and understand SEs in other cell-types.
Low socioeconomic status (SES) in childhood may be associated with sleep in adulthood.
Low socioeconomic status (SES) in childhood associates with poor sleep quality in adulthood.
Taken together, these results suggest that Smad3 is the most informative feature to distinguish SEs in differentiated cells, but this needs further validation in other differentiated cell-types.
Taken together, our systematic analysis and ranking of features can be used as a platform to define and understand the biology of SEs in other cell-types.
We also showed that Cdk8 and Cdk9 can define known and new SEs in mESC, which further validates their importance in the SE formation and cell identity.
