SACC-M cells are highly invasive and tumorigenic isolated from a SACC cell line SACC-2 that derived from human minor salivary gland in palate.
However, solid SACC lack of proteoglycans had the worst survival rate in all kinds of SACC [ 29, 35- 38].
Our studies confirm that MTUS1 plays an important role in the progression of SACC, and may serve as a biomarker or therapeutic target for patients with SACC.
We found that MTUS1 down-regulation is associated with poor prognosis in SACC; MTUS1/ATIP3a down-regulation contributes to the proliferation, migration and the invasion abilities of SACC, which involved extracellular signal-regulated kinase 1/2 (ERK1/2 -Slug signaling.
Thus, our results provide evidence suggesting a critical role of MTUS1/ATIP in the tumorigenesis of SACC, and MTUS1/ATIP3a may serve as a biomarker or a novel therapeutic target for patients with SACC.
& Hans., and Sclerotium rolfsii Sacc.
In this study, we investigated the role of GPC5 in the lung metastasis of SACC.
The scaffolds obtained during this procedure were designated as SACCH and SACC.
Moreover, the Young's modulus of SACCH and SACC were 200.8 and 18.61, respectively.
The higher transition temperature suggests that SACCH and SACC have high stability at high-temperature environment.
