Spinal neurons distributed over the superficial laminae (laminae I-III) respond to nociceptive stimuli, and these neurons directly contribute to the transmission of nociception [33].
C-fos mRNA was observed in the spinal cord after the formalin test, and expression peaked at 15 30 minutes in the superficial laminae of dorsal horn (laminae I II) and at 30 60 minutes in the deep laminae (laminae V VI).
A previous study identified c-fos mRNA in the spinal cord after the formalin test, and expression of c-Fos peaked at 30 min in the superficial laminae of the dorsal horn (laminae I II) and at 1 3 h in the deep laminae (laminae V VI) [ 7].
The labeling appeared to be widespread across dorsal horn laminae I-V, with the most prominent increase observed in laminae III-IV (Fig. 4A).
Now, we just basically made a little trench and got him down to the wall, just about to the laminae; that's the sensitive part of the hoof.
These laminae show us a chronosequence of events, alternating between mineral deposition and organic layer growth.
Plywood and laminated wood are both made of layers (laminae) of wood glued together.
organum vasculosum laminae terminalis.
Mid-veins and leaf laminae.
Therefore, the superficial laminae have more crucial roles in neuropathic pain compared to the deep laminae.
