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Among the IRF family members, IRF-5 and IRF-7 share the same signaling pathway that is initiated through TLR7/8 and TLR9 [11] [11].
One unexpected finding in these IRF siRNA knockdown experiments was that IRF-3 was not required for IFN induction.
IRF: IRF indicates the usage of the internal register file.
The instrument response function (IRF) is included λem = 591 nm.
The instrument response function (IRF) is also included.
We call our approach, instruction register file (IRF).
Similar(32)
The difference between IRF-1 and IRF-7 on HIV-1 replication may be due to the requirement of IRF-1, but not IRF-7, for full NF-κB transcriptional activity at the HIV-1 long term repeat enhancer [53].
Wang et al. reported that JNK1 stimulated XAF1 promoter activity through IRF-1 expression in gastrointestinal cancer in which IRF-1 bound to IRF-E within XAF1 promoter.
Plasmid DNA encoding IRF-1, but not IRF-3 or IRF-7, enhanced antigen-specific immune responses.
LPS induced IRF-7, but reduced PPARd expression; whereas DMPO reduced IRF-7, but induced PPAR-d expression.
And an IRF-7C mutant, IRF-7CK92E had no effects.
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