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All these target neurons express the specific receptors for GRP (GRP-R).
The released GRP subsequently activate GRP receptor-expressing neurons to relay itch information from the periphery to the brain [42].
The synthetic carotenoid derivatives studied were the Girard's reagent P derivative (GRP) of retinal (GRP-retinal), the GRP derivative of β-apo-8′-carotenal (GRP-carotenal), the Girard's reagent T derivative of β-apo-8′-carotenal (GRT-carotenal), the GRP derivative of canthaxanthin ((GRP 2-canthaxanthin) and the dansyl hydrazine derivative of β-apo-8′-carotenal (dansyl-carotenal).
* BUZZCOCKS, KUNST PS, STEVE DIGGLE GRP, Bowery Ballroom, 6 Delancey Street, Lower East Side, (212) 212-4700.
SPS also attenuated two aspects of the GRP system, the expression of GRP per se and the expression of ARs that regulate penile reflexes.
We also explored the use of quadratic terms of GRP to explore possible non-linear relationships between GRP and counts of the road safety-related health outcomes.
P < 0.05 for pairwise comparisons except: GRP versus GDACNTF for GDNF, BDNF, IGF1 and GRP versus GDABMP for Neurturin).
Concurrently, ICV injection of GRP produced an increase in systolic and diastolic PDA and consequently GRP caused an increase in mean PDA.
GRP binds preferentially to a G-protein coupled receptor designated as GRP receptor (GRPR, also called BB2) (Lehmann and Beglinger, 2006; Roesler and Schwartsmann, 2012).
GRP-like immunoreactivity is widely distributed throughout the mammalian gastrointestinal tract and GRP affects several gastrointestinal functions including motility, and endocrine and exocrine secretions.
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In the CHO-GRP cells, GRP produced a concentration-dependent increase in [Ca2+]i (EC50=2.00±0.4 n M, n=5, Figure 5A).
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