Sentence examples for * enl in from inspiring English sources

Our data revealed important alterations in the IGF system in relation to the status of the host immune-inflammatory response to ML while at the same time pointing to the circulating IGF-I/IGFBP-3 levels as possible predictive biomarkers for ENL in LL patients at diagnosis.

The possible biological mechanism is not clear, but in vitro studies also showed that lignan ENL in the presence of oestrogens suppressed the oestrogen-induced proliferation in MCF-7 breast cancer cell (Mousavi and Adlercreutz, 1992) and stimulated the synthesis of sex hormone-binding globulin in liver cells (Adlercreutz et al, 1992).

Although MLL-N ChIP cannot specifically detect MLL-AF9 or MLL-ENL, in combination with the data in Figure 3, we think the most likely explanation for these results is that MLL-AF4 differs from other MLL-FPs and increases stable AF9 and ENL binding at RUNX1.

We have applied our approach to genes involved in 11q23 translocations (MLL, AF4 and ENL genes) in differentiated haematological cell lineages by 3D-FISH and in-depth image data analysis.

A recent paper demonstrate that AF4, AF5q31 and ENL associate in an endogenous higher-order complex containing P-TEFb in haemopoietic lineage cells [ 16].

RR predominates in BL patients with a bacilloscopic index (BI) below 3 while ENL occurs in LL patients with high BI [ 5, 6].

This behavior explains the small ENL reduction in the case of the proposed method.

Using triple labeling 3D FISH experiments, we have determined the relative positions of MLL, AF4 and ENL genes, in two lymphoblastic and two myeloid human cell lines.

The type 2 reaction or erythema nodosum leprosum (ENL) occurs in multibacillary patients (BL and LL) with low cellular immune responses and is related to the deposition of immune complexes in response to M. leprae antigens [ 5, 6].

Nonetheless, the DG4P was less affected by this negative effect of hypoglycaemia on sensor accuracy than the ENL and outperformed ENL in all glycaemic ranges.

Both these genes are required for efficient in vitro myeloid immortalization by MLL-ENL and in a bone marrow transplantation model Hoxa9 is essential for MLL-dependent leukemogenesis in vivo [52].