DFS and OS were analysed for DTH <10 mm (negative or weak DTH) vs DTH ⩾10 mm (strong positive DTH).
DTH testing is a valuable measure of CMI since the DTH test is an in vivo test and DTH responses are by definition anamnestic responses.
Piglets were subject to DTH testing only once to avoid the possibility of the DTH antigens influencing subsequent DTH test results.
The median survival time of patients who became positive for DTH (16.6 months) was eight months longer than that of DTH-negative patients (8.2 months).
Those with a positive DTH were found to live longer than those that did not have a positive DTH [ 105].
DTH skin test reactivity, measured by anergy, the number of positive antigens, and the combined DTH response induration, was significantly related to the clinical stage of HIV disease.
Vaccinated patients that became DTH positive had significantly improved survival rates (71% 5-year survival) compared to patients that remained DTH negative (49% 5-year survival).
Silver et al did not get robust DTH without PTX although in our hands mice immunized with MOG161 180 peptide and CFA (without PTX) did develop robust DTH.
The DTH index was calculated as the number of positive DTH responses to LNCaP lysate divided by the total number of DTH time points for each patient.
Their rallying call is data, not DTH.
Rats with adoptive DTH were humanely euthanized immediately after DTH measurement.
