* P ≤0.01 when type II collagen (CII) responses from A12-treated mice were compared with CII responses from untreated mice.
The antigen specificity of 1-11E/vIL-10 fusion proteins was determined with ELISA, by using native CII (NT CII), ROS-CII (CII modified by glycation (GLY) and HOCl (HOCl)), or control HEL as target antigens.
Clearly, immunization with heterologous CII activates both CII-reactive T cells and B cells.
Hence, to demonstrate the autonomous role of CII in cell death induction, functional CII is required.
To confirm that the increase in respiration is specifically due to respiration through CII, a cell-permeable prodrug of the CII inhibitor malonate, NV01-161, (NV161, diacetoxymethyl malonate, Fig. 1h) was designed, synthesized and evaluated (Supplementary Fig. 2).
In the MOI = 2 infection CII must dominate Lyt, but in the MOI = 1 infection Lyt must dominate CII.
According to the CII web site, it is only accessible to CII members.
Succinate is a mitochondrial substrate metabolized through complex II (CII).
CII Technologies, a unit of the closely held CIIT Holding Inc., makes electric relays, transformers and filters under the CII, Hartman and Kilovac brand names, the companies said.
N. 10th St . Buildings etc. Send for Cii cular.
Circulating serum levels of anti-mouse CII antibody (Chondrex) and Nampt (AdipoGen®) were determined by ELISA.
